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. 2019 Nov;32(4):378–384. doi: 10.2337/ds18-0069

TABLE 1.

Overview of InPen, ESYSTA, Pendiq, and YpsoMate SmartPilot Smart Insulin Pens

InPen ESYSTA Pendiq YpsoMate SmartPilot
Company Companion Medical Emperra Pendiq YpsoMed
Country of origin United States Germany Germany Switzerland
FDA approval 2016 No No No
U.S. availability Yes No No No
Cost $665 $220 (€192)* $193 (€169)* Unable to verify
Insulin compatibilities Lispro/aspart 3-mL cartridges Lispro/aspart/glulisine 3-mL cartridges Lispro/aspart 3-mL cartridges Prefilled insulin
App service Apple, Android Apple, Android Apple, Android Unable to verify
Bluetooth Yes Yes Yes Yes
USB No No Yes No
Features • Lasts 1 year
• Temperature sensor
• Dose calculator
• Reminders for patient
• Prescription needed
• Cloud database accessible to providers
• Replaceable batteries (last for up to 1 year)
• Memory capacity for 1,000 data records
• Memory for recording last 1,000 injections (date, time, quantity)
• Alarms if low battery, needle blockage, or low insulin
• Rechargeable battery
• Tracks injection time and sequence of handling (pressing against skin, triggering the injection, positioning the injector, end of injection)
*

Currency conversions conducted on 29 January 2019.