Table 1.

Effects of age, period and birth cohort on mortality due to viral hepatitis, primary liver cancer and chronic liver disease in mainland China

	Viral hepatitis			Primary liver cancer			Chronic liver disease
	Coefficient	95% CI	P value	Coefficient	95% CI	P value	Coefficient	95% CI	P value
Intercept	−11.34	−11.49 to −11.2	<0.001	−9.25	−9.49 to −9.01	<0.001	−9.95	−10.08 to −9.83	<0.001
Age (in group)
5–9	−1.38	−1.68 to −1.08	<0.001	−3.33	−4.07 to −2.6	<0.001	−2.83	−3.29 to −2.38	<0.001
10–14	−1.63	−1.89 to −1.36	<0.001	−3.05	−3.59 to −2.51	<0.001	−2.65	−3.01 to −2.3	<0.001
15–19	−1.56	−1.78 to −1.35	<0.001	−2.35	−2.72 to −1.98	<0.001	−2.25	−2.51 to −1.99	<0.001
20–24	−1.32	−1.49 to −1.15	<0.001	−1.71	−1.98 to −1.44	<0.001	−1.49	−1.67 to −1.3	<0.001
25–29	−1.01	−1.16 to −0.87	<0.001	−1.00	−1.21 to −0.79	<0.001	−1.09	−1.24 to −0.93	<0.001
30–34	−0.67	−0.79 to −0.55	<0.001	−0.25	−0.41 to −0.08	0.003	−0.45	−0.58 to −0.33	<0.001
35–39	−0.33	−0.42 to −0.23	<0.001	0.23	0.1 to 0.36	0.001	0.00	−0.1 to 0.1	0.928
40–44	0.00	−0.08 to 0.08	0.930	0.63	0.53 to 0.74	<0.001	0.46	0.38 to 0.54	<0.001
45–49	0.16	0.09 to 0.24	<0.001	0.85	0.76 to 0.94	<0.001	0.75	0.68 to 0.82	<0.001
50–54	0.46	0.38 to 0.53	<0.001	1.08	1 to 1.17	<0.001	1.00	0.93 to 1.06	<0.001
55–59	0.62	0.54 to 0.7	<0.001	1.20	1.11 to 1.29	<0.001	1.10	1.03 to 1.16	<0.001
60–64	0.84	0.75 to 0.93	<0.001	1.35	1.24 to 1.45	<0.001	1.24	1.17 to 1.32	<0.001
65–69	1.06	0.95 to 1.16	<0.001	1.47	1.33 to 1.6	<0.001	1.38	1.29 to 1.47	<0.001
70–74	1.35	1.23 to 1.48	<0.001	1.59	1.43 to 1.76	<0.001	1.53	1.42 to 1.64	<0.001
75–79	1.60	1.45 to 1.74	<0.001	1.63	1.43 to 1.82	<0.001	1.62	1.49 to 1.75	<0.001
80–84	1.81	1.64 to 1.98	<0.001	1.66	1.43 to 1.89	<0.001	1.69	1.53 to 1.84	<0.001
Period (calendar year)
1987–1991	0.36	0.3 to 0.43	<0.001	−0.17	−0.27 to −0.08	<0.001	0.18	0.12 to 0.25	<0.001
1992–1996	0.07	0.01 to 0.12	0.016	−0.11	−0.17 to −0.05	0.001	0.16	0.11 to 0.2	<0.001
1997–2001	−0.08	−0.13 to −0.03	0.001	0.03	0 to 0.07	0.060	0.16	0.13 to 0.19	<0.001
2002–2006	−0.39	−0.44 to −0.34	<0.001	0.08	0.05 to 0.12	<0.001	0.10	0.07 to 0.13	<0.001
2007–2011	−0.09	−0.15 to −0.04	<0.001	0.11	0.05 to 0.17	<0.001	−0.21	−0.25 to −0.16	<0.001
2012–2016	0.13	0.07 to 0.19	<0.001	0.05	−0.04 to 0.14	0.246	−0.40	−0.47 to −0.34	<0.001
Birth cohort (birth year)
1907	0.16	−0.15 to 0.48	0.304	1.01	0.69 to 1.33	<0.001	1.15	0.95 to 1.35	<0.001
1912	0.23	0.01 to 0.45	0.037	0.99	0.74 to 1.25	<0.001	1.04	0.89 to 1.19	<0.001
1917	0.32	0.15 to 0.5	<0.001	1.00	0.78 to 1.22	<0.001	0.98	0.86 to 1.11	<0.001
1922	0.52	0.37 to 0.67	<0.001	1.03	0.83 to 1.23	<0.001	0.95	0.85 to 1.06	<0.001
1927	0.66	0.52 to 0.79	<0.001	1.03	0.84 to 1.22	<0.001	0.89	0.79 to 0.98	<0.001
1932	0.72	0.59 to 0.84	<0.001	0.95	0.76 to 1.13	<0.001	0.76	0.67 to 0.85	<0.001
1937	0.72	0.59 to 0.84	<0.001	0.82	0.63 to 1.01	<0.001	0.59	0.5 to 0.69	<0.001
1942	0.76	0.63 to 0.9	<0.001	0.70	0.5 to 0.9	<0.001	0.45	0.35 to 0.56	<0.001
1947	0.87	0.73 to 1.01	<0.001	0.67	0.46 to 0.89	<0.001	0.40	0.29 to 0.52	<0.001
1952	0.92	0.77 to 1.07	<0.001	0.62	0.39 to 0.86	<0.001	0.33	0.19 to 0.46	<0.001
1957	0.82	0.65 to 0.98	<0.001	0.37	0.12 to 0.63	0.005	0.16	0.01 to 0.32	0.033
1962	0.80	0.62 to 0.98	<0.001	0.24	−0.04 to 0.52	0.097	0.09	−0.08 to 0.26	0.295
1967	0.77	0.57 to 0.96	<0.001	0.11	−0.2 to 0.42	0.470	0.11	−0.08 to 0.3	0.258
1972	0.54	0.33 to 0.76	<0.001	−0.18	−0.52 to 0.16	0.308	−0.10	−0.32 to 0.11	0.349
1977	0.18	−0.07 to 0.42	0.152	−0.52	−0.89 to −0.14	0.007	−0.47	−0.72 to −0.23	<0.001
1982	−0.12	−0.39 to 0.15	0.375	−0.73	−1.15 to −0.3	0.001	−0.86	−1.15 to −0.56	<0.001
1987	−0.49	−0.82 to −0.17	0.003	−0.75	−1.23 to −0.27	0.002	−0.97	−1.32 to −0.62	<0.001
1992	−0.95	−1.37 to −0.54	<0.001	−1.15	−1.75 to −0.55	<0.001	−1.13	−1.57 to −0.69	<0.001
1997	−1.81	−2.55 to −1.08	<0.001	−1.28	−2.14 to −0.42	0.004	−1.29	−1.97 to −0.61	<0.001
2002	−2.76	−4.22 to −1.3	<0.001	−2.53	−4.94 to −0.12	0.040	−1.98	−3.45 to −0.5	0.009
2007	−2.84	−4.95 to −0.72	0.009	−2.41	−6.27 to 1.44	0.220	−1.12	−2.81 to 0.58	0.196