Table 2.
Variable | Death n=39 | Nursing home transfer n=48 | Hospital admission n=93 | |||||||||
HR | Lower limit | Upper limit | P value | HR | Lower limit | Upper limit | P value | HR | Lower limit | Upper limit | P value | |
CFS (6-7/4-5) | 5.92 | 3.12 | 11.22 | <0.001 | 6.00 | 3.37 | 10.66 | <0.001 | 2.92 | 1.93 | 4.40 | <0.001 |
EQ-5D (Q1/Q5) | 6.26 | 2.11 | 18.62 | 0.006 | 3.18 | 1.29 | 7.82 | 0.02 | 2.94 | 1.47 | 5.87 | 0.004 |
EQ-VAS (Q1/Q5) | 7.00 | 2.34 | 20.93 | 0.003 | 3.38 | 1.22 | 9.35 | 0.03 | 6.69 | 3.20 | 13.99 | <0.001 |
MoCA (Q1/Q5) | 1.28 | 0.35 | 4.75 | 0.71 | 4.56 | 1.81 | 11.49 | 0.007 | 2.03 | 0.97 | 4.28 | 0.07 |
GDS (>2/<2) | 1.63 | 0.66 | 4.05 | 0.23 | 3.22 | 1.55 | 6.66 | <0.001 | 2.45 | 1.18 | 5.10 | 0.02 |
Gait speed (Q1/Q5) | 5.87 | 1.78 | 19.34 | <0.001 | 8.51 | 3.18 | 22.79 | <0.001 | 11.05 | 5.45 | 22.40 | <0.001 |
Grip strength (Q1/Q4) | 10.50 | 3.66 | 30.33 | 0.004 | 10.61 | 3.57 | 31.52 | 0.003 | 1.88 | 0.94 | 3.78 | 0.08 |
WST (fail/pass) | 1.90 | 0.66 | 5.45 | 0.46 | 2.74 | 1.02 | 7.35 | 0.01 | 1.53 | 0.86 | 2.75 | 0.12 |
MNA-SF (Q1/Q5) | 8.40 | 1.87 | 37.76 | 0.02 | 12.52 | – | – | 0.001 | 5.95 | 2.66 | 13.27 | 0.001 |
Haemoglobin (Q1/Q5) | 8.34 | 3.12 | 22.31 | 0.001 | 0.88 | 0.38 | 2.05 | 0.77 | 2.27 | 1.14 | 4.52 | 0.02 |
eGFR (Q1/Q5) | 5.65 | 2.30 | 13.90 | 0.002 | 1.59 | 0.66 | 3.82 | 0.30 | 2.45 | 1.28 | 4.72 | 0.01 |
HgbA1c (Q1/Q5) | 0.62 | 0.23 | 1.66 | 0.74 | 0.42 | 0.08 | 2.08 | 0.63 | 1.34 | 0.65 | 2.75 | 0.06 |
Diseases (yes/no) | ||||||||||||
Neurological | 1.5 | 0.79 | 2.84 | 0.24 | 1.47 | 0.82 | 2.61 | 0.22 | 1.56 | 1.03 | 2.36 | 0.046 |
Respiratory | 1.71 | 0.81 | 3.62 | 0.11 | 1.4 | 0.71 | 2.75 | 0.28 | 1.3 | 0.79 | 2.13 | 0.27 |
Cardiac | 3.7 | 1.92 | 7.14 | 0.003 | 1.8 | 1 | 3.27 | 0.08 | 2.45 | 1.6 | 3.75 | 0.001 |
Hypertension | 1.14 | 0.6 | 2.15 | 0.70 | 0.65 | 0.36 | 1.15 | 0.13 | 0.96 | 0.63 | 1.45 | 0.085 |
Cancer- active | 2.66 | 0.99 | 7.11 | 0.006 | 1.31 | 0.54 | 3.16 | 0.51 | 1.41 | 0.72 | 2.76 | 0.24 |
Osteoporotic fracture | 0.57 | 0.3 | 1.08 | 0.12 | 0.89 | 0.5 | 1.6 | 0.71 | 1.11 | 0.73 | 1.68 | 0.63 |
Osteoarthritis /chronic pain | 1.39 | 0.73 | 2.63 | 0.33 | 1.15 | 0.64 | 2.04 | 0.65 | 1.59 | 1.05 | 2.39 | 0.04 |
Dementia | 1.16 | 0.6 | 2.23 | 0.66 | 5.72 | 3.16 | 10.38 | <0.001 | 1.49 | 0.97 | 2.29 | 0.05 |
Mood disorder | 0.87 | 0.46 | 1.63 | 0.66 | 2.26 | 1.28 | 3.98 | 0.007 | 1.51 | 1.01 | 2.27 | 0.48 |
Multiple comorbidities | 3.29 | 1.37 | 7.90 | 0.08 | 2.68 | 1.22 | 5.90 | 0.09 | 3.96 | 2.25 | 6.99 | 0.004 |
Number of drugs (Q5/Q1) | 3.55 | 0.96 | 13.10 | 0.09 | 2.01 | 0.75 | 5.39 | 0.26 | 6.09 | 2.93 | 12.69 | <0.001 |
CFS, Clinical Frailty Scale; eGFR, estimated glomerular filtration rate; EQ-5D, EuroQol EQ-5D-5L; EQ-VAS, EuroQol Visual Analogue Scale; GDS, Geriatric Depression Scale; HgbA1c, haemoglobin A1c; MNA-SF, Mini-Nutritional Assessment; MoCA, Montreal Cognitive Assessment; WST, water swallow test.