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. 2019 Nov 12;9(11):e032712. doi: 10.1136/bmjopen-2019-032712

Table 2.

Predictors of death, nursing home transfer and hospital admission – HRs and 95% CIs

Variable Death n=39 Nursing home transfer n=48 Hospital admission n=93
HR Lower limit Upper limit P value HR Lower limit Upper limit P value HR Lower limit Upper limit P value
CFS (6-7/4-5) 5.92 3.12 11.22 <0.001 6.00 3.37 10.66 <0.001 2.92 1.93 4.40 <0.001
EQ-5D (Q1/Q5) 6.26 2.11 18.62 0.006 3.18 1.29 7.82 0.02 2.94 1.47 5.87 0.004
EQ-VAS (Q1/Q5) 7.00 2.34 20.93 0.003 3.38 1.22 9.35 0.03 6.69 3.20 13.99 <0.001
MoCA (Q1/Q5) 1.28 0.35 4.75 0.71 4.56 1.81 11.49 0.007 2.03 0.97 4.28 0.07
GDS (>2/<2) 1.63 0.66 4.05 0.23 3.22 1.55 6.66 <0.001 2.45 1.18 5.10 0.02
Gait speed (Q1/Q5) 5.87 1.78 19.34 <0.001 8.51 3.18 22.79 <0.001 11.05 5.45 22.40 <0.001
Grip strength (Q1/Q4) 10.50 3.66 30.33 0.004 10.61 3.57 31.52 0.003 1.88 0.94 3.78 0.08
WST (fail/pass) 1.90 0.66 5.45 0.46 2.74 1.02 7.35 0.01 1.53 0.86 2.75 0.12
MNA-SF (Q1/Q5) 8.40 1.87 37.76 0.02 12.52 0.001 5.95 2.66 13.27 0.001
Haemoglobin (Q1/Q5) 8.34 3.12 22.31 0.001 0.88 0.38 2.05 0.77 2.27 1.14 4.52 0.02
eGFR (Q1/Q5) 5.65 2.30 13.90 0.002 1.59 0.66 3.82 0.30 2.45 1.28 4.72 0.01
HgbA1c (Q1/Q5) 0.62 0.23 1.66 0.74 0.42 0.08 2.08 0.63 1.34 0.65 2.75 0.06
Diseases (yes/no)
 Neurological 1.5 0.79 2.84 0.24 1.47 0.82 2.61 0.22 1.56 1.03 2.36 0.046
 Respiratory 1.71 0.81 3.62 0.11 1.4 0.71 2.75 0.28 1.3 0.79 2.13 0.27
 Cardiac 3.7 1.92 7.14 0.003 1.8 1 3.27 0.08 2.45 1.6 3.75 0.001
 Hypertension 1.14 0.6 2.15 0.70 0.65 0.36 1.15 0.13 0.96 0.63 1.45 0.085
 Cancer- active 2.66 0.99 7.11 0.006 1.31 0.54 3.16 0.51 1.41 0.72 2.76 0.24
 Osteoporotic fracture 0.57 0.3 1.08 0.12 0.89 0.5 1.6 0.71 1.11 0.73 1.68 0.63
 Osteoarthritis /chronic pain 1.39 0.73 2.63 0.33 1.15 0.64 2.04 0.65 1.59 1.05 2.39 0.04
 Dementia 1.16 0.6 2.23 0.66 5.72 3.16 10.38 <0.001 1.49 0.97 2.29 0.05
Mood disorder 0.87 0.46 1.63 0.66 2.26 1.28 3.98 0.007 1.51 1.01 2.27 0.48
Multiple comorbidities 3.29 1.37 7.90 0.08 2.68 1.22 5.90 0.09 3.96 2.25 6.99 0.004
Number of drugs (Q5/Q1) 3.55 0.96 13.10 0.09 2.01 0.75 5.39 0.26 6.09 2.93 12.69 <0.001

CFS, Clinical Frailty Scale; eGFR, estimated glomerular filtration rate; EQ-5D, EuroQol EQ-5D-5L; EQ-VAS, EuroQol Visual Analogue Scale; GDS, Geriatric Depression Scale; HgbA1c, haemoglobin A1c; MNA-SF, Mini-Nutritional Assessment; MoCA, Montreal Cognitive Assessment; WST, water swallow test.