Table 5.
Summary of shifts from baseline to week 105 for haematology and fasting lipid profile values
| Analyte (unit) | Patients (n) | Mean change | Standard deviation |
|---|---|---|---|
| Haematology values | |||
| ANC (106/l) | 549 | − 353.1 | 2293.74 |
| Neutrophils (%) | 552 | − 1.01 | 9.559 |
| Basophils (106/l) | 549 | 5.7 | 27.03 |
| Basophil/leukocyte fraction | 552 | 0.0011 | 0.00352 |
| Eosinophils (106/l) | 549 | 4.8 | 213.30 |
| Eosinophil/leukocyte fraction | 552 | 0.0012 | 0.01733 |
| Haematocrit fraction | 543 | 0.0134 | 0.03674 |
| Haemoglobin (g/l) | 549 | 1.0 | 11.41 |
| Lymphocytes (106/l) | 549 | − 154.6 | 687.43 |
| Lymphocyte/leukocyte fraction | 552 | − 0.0046 | 0.08525 |
| Monocytes (106/l) | 549 | 57.8 | 202.63 |
| Monocyte/leukocyte fraction | 552 | 0.0121 | 0.02363 |
| Platelets (109/l) | 549 | 10.5 | 67.48 |
| Erythrocytes (1012/l) | 549 | 0.097 | 0.3098 |
| Leukocytes (109/l) | 549 | − 0.44 | 2.672 |
| Fasting lipid profile values (mmol/l) | |||
| Cholesterol | 315 | 0.266 | 0.9781 |
| HDL cholesterol | 315 | 0.213 | 0.3341 |
| LDL cholesterol | 311 | 0.060 | 0.7566 |
| Triglycerides | 314 | − 0.051 | 1.4337 |
All shift data are reported as shift from this long-term extension study baseline to week 105
ANC absolute neutrophil count, HDL high-densty lipoprotein, LDL low-density lipoprotein