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. Author manuscript; available in PMC: 2020 Apr 2.
Published in final edited form as: Nature. 2019 Oct 2;574(7777):273–277. doi: 10.1038/s41586-019-1618-0

Fig. 1 |. Frequent co-existing IDH2 and SRSF2 mutations in acute myeloid leukemia (AML).

Fig. 1 |

a, Heatmap of ΔPSI (Percent-Spliced-In) values for mutant SRSF2-specific splicing events in TCGA AML samples. b-d, Co-occurrence of mutations in IDH1/2, TET2, and RNA splicing factors in the TCGA (b), Beat-AML (c), and Leucegene (d) cohorts (number of patients indicated; co-occurrence or exclusivity noted by color-coding; Fisher’s exact test (two-sided)).