Skip to main content
. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Nat Genet. 2019 Nov 1;51(11):1574–1579. doi: 10.1038/s41588-019-0519-3

Figure 5. Genome-wide polygenic risk score and incident VTE events.

Figure 5.

Hazard ratios calculated from the Cox Proportional hazards model for incident VTE events in the Women’s Health Initiative study for carriers of the F5 p.R506Q and F2 G20210A mutations. The hazard ratio for individuals with the highest 5% PRSVTE compared to individuals among the lower 95% of PRSVTE is also depicted. Two-sided values of P are displayed.

Abbreviations: VTE, Venous Thromboembolism; PRS, Polygenic Risk Score; Chr, Chromosome; CI, Confidence Interval