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4′,6-diamidine-2′-phenylindole dihydrochloride (DAPI) for nuclear staining (blue), nuclear factor erythroid 2-related factor 2 (Nrf2) (green), and merged DAPI/Nrf2 in the cortex of sham, vehicle, and dimethyl fumarate (DMF)-treated groups; the increased number of nuclei and Nrf2 expression can be seen in the DMF-treated group in comparison with vehicle group.
