Table 1.
Vaccine (dose) | Mean ± SD of log10 CFU in spleen of: | Units of protection | |
---|---|---|---|
B. ovis | Vaccine | ||
Rev1 (105) | 2.45 ± 1.35a | 2.82 ± 0.99 | 3.81 |
Rev1::Tn7wbdRΔwbkC (105) | 4.47 ± 1.40 | 0.69 ± 0.09c | 1.79 |
Rev1::Tn7wbdRΔwbkC (108) | 2.16 ± 0.95a, b | 0.90 ± 0.53c | 4.10 |
PBS (unvaccinated) | 6.26 ± 0.16 | 0.00 |
Statistical comparison (n = 5) of mean log10 B. ovis CFU/spleen: ap < 0.001 vs. PBS (unvaccinated), bp > 0.05 vs. Rev1 and log10 vaccine CFU/spleen c p < 0.01 vs. Rev1.