Skip to main content
. 2019 Nov 15;17:148. doi: 10.1186/s12964-019-0463-y

Table 1.

Different NFATC1 forms and mutants used in the experiments

NFATC1 proteins Mutated sites Length
Wild type (WT) none full-length
Dominant negative (DN) none 410–680 aa
Constitutively active (mSRR) all 11 serines mutated to alanines in the SRR (172–194) 1–418 aa
Double mutant (DM) S245, S269 full-length
Triple mutant (TM) S151, S153, T154, S256, S257, S335, T338, T339 full-length
Multi mutant (MM) S151, S153, T154, S245, S256, S257, S269, S335, T338, T339 full-length

The amino acid substitutions (from serine or threonine to alanine) and other mutations in NFATC1 and the length of each mutant protein used in this study