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. 2019 Nov 15;18:156. doi: 10.1186/s12933-019-0960-8

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Main and sensitivity analyses of treatment differences in time to first hHF (SMQ definition). *Broad MedDRA search weighted by proportion confirmed in LEADER by the Event Adjudication Committee. There were only 100 events using the broad MedDRA search without the LEADER match, 31 of which were classed as cardiac disorders. CI confidence interval, glargine U100 insulin glargine 100 units/mL, hHF hospitalization for heart failure, HF heart failure, N number of patients, % proportion of patients, SMQ standardized Medical Dictionary for Regulatory Activities Query