Table 1. Characteristics of miRNA interaction in the mRNA of BC subtype triple-negative.
| Gene, RPKM | miRNA | Start of binding site, nt | ΔG, kJ/mole | ΔG/ΔGm, % | Length, nt |
|---|---|---|---|---|---|
| CBL | ID03332.3p-miR (4) | 16 ÷ 25 | −134 ÷−140 | 90 ÷ 94 | 24 |
| 3.9 | ID01310.3p-miR (4) | 17 ÷ 26 | −121 | 92 | 22 |
| ID02761.3p-miR | 28 | −138 | 93 | 24 | |
| miR-1908-3p | 30 | −121 | 92 | 21 | |
| ID00278.3p-miR | 32 | −125 | 91 | 23 | |
| ID02430.3p-miR | 34 | −110 | 98 | 18 | |
| MMP2 | ID00278.3p-miR | 110 | −123 | 89 | 23 |
| 192.4 | ID01310.3p-miR | 113 | −121 | 92 | 22 |
| ID03037.3p-miR | 115 | −121 | 90 | 22 | |
| ID03345.5p-miR | 124 | −127 | 90 | 24 | |
| ID03368.3p-miR | 125 | −117 | 89 | 23 | |
| RAB5A | ID02930.3p-miR | 184 | −132 | 89 | 24 |
| 16.1 | ID03445.3p-miR | 189 | −127 | 90 | 24 |
| ID01859.5p-miR | 191 | −121 | 89 | 23 | |
| ID01804.3p-miR | 325 | −140 | 88 | 25 | |
| ID03367.5p-miR | 328 | −121 | 97 | 20 | |
| ID00061.3p-miR | 334 | −127 | 92 | 22 | |
| ATM** | ID03006.5p-miR | 9,778 | −121 | 89 | 24 |
| 3.9 | miR-5095 | 9,787 | −108 | 93 | 21 |
| miR-619-5p | 9,793 | −119 | 98 | 22 | |
| miR-1273a | 11,054 | −119 | 90 | 25 | |
| miR-1273g-3p | 11,076 | −113 | 96 | 21 | |
| ID00367.5p-miR | 11,069 | −110 | 90 | 22 | |
| CBL** | miR-1273a | 7,727 | −117 | 89 | 25 |
| miR-1273g-3p | 7,749 | −115 | 98 | 21 | |
| 3.9 | ID01838.5p-miR | 7,728 | −117 | 93 | 24 |
| IL11** | miR-1273f | 1,466 | −102 | 98 | 19 |
| 0.1 | miR-1273d | 1,467 | −121 | 89 | 25 |
| miR-1273e | 1,476 | −113 | 96 | 22 | |
| ID01404.5p-miR | 1,470 | −113 | 91 | 23 | |
| RUNX1** | miR-466 (2) | 5,456 ÷ 5,460 | −106 ÷ -110 | 91 ÷ 95 | 23 |
| 9.0 | ID01030.3p-miR (2) | 5,454 ÷ 5,464 | −108 ÷−113 | 89 ÷ 93 | 23 |
| D00436.3p-miR | 5,464 | −108 | 93 | 23 | |
| SFN** | miR-6089 | 826 | −129 | 87 | 24 |
| 9.4 | ID01774.5p-miR | 835 | −129 | 90 | 23 |
| miR-6846-5p | 839 | −113 | 91 | 22 | |
| ID00790.3p-miR | 1,179 | −104 | 89 | 23 | |
| ID02868.3p-miR | 1,188 | −113 | 90 | 23 | |
| miR-466 (6) | 1,190 ÷ 1,200 | −106 | 91 | 23 | |
| ID01030.3p-miR (6) | 1,190 ÷ 1,200 | −108 | 89 | 23 | |
| ID00436.3p-miR (7) | 1,190 ÷ 1,202 | −104 | 89 | 23 | |
| ID01727.5p-miR (2) | 1,203 ÷ 1,205 | −104 ÷−106 | 89 ÷ 91 | 23 | |
| ID02882.3p-miR | 1,210 | −108 | 91 | 21 | |
| STMN1** | miR-1273a | 1,729 | −115 | 87 | 25 |
| miR-1273g-3p | 1,751 | −108 | 93 | 21 | |
| ID00367.5p-miR | 1,744 | −113 | 91 | 22 | |
| 6.6 | ID03011.5p-miR | 1,730 | −106 | 91 | 22 |
Notes.
Genes without *—miRNA binding sites are in the 5′UTR, genes with *—miRNA binding sites are in the CDS, **—miRNA binding sites are in the 3′UTR; values in parentheses indicate the number of binding sites; ÷—the change of the parameter in the interval. Different repeating clusters of miRNA binding sites in different genes are coloured.