. 2019 Nov 13;7:e8049. doi: 10.7717/peerj.8049

Table 3. Characteristics of miRNA interaction in mRNA genes of BC subtype HER2.

Gene, RPKM	miRNA	Start of binding site, nt	ΔG, kJ/mole	ΔG/ΔGm, %	Length, nt
EPOR	ID01633.3p-miR	77	−108	91	21
8.1	ID01599.3p-miR	79	−119	89	23
8.1	ID01626.3p-miR	80	−129	90	23
MAZ	ID00968.3p-miR	16	−117	93	20
9.5	ID01476.3p-miR	16	−134	91	23
	miR-1470	18	−123	97	21
	ID00620.3p-miR	27	−127	91	23
	miR-6850-5p	92	−115	87	22
	miR-4466	107	−110	98	18
	miR-762	111	−123	91	22
	D00915.3p-miR	112	−127	88	24
	ID02979.5p-miR	114	−121	92	22
NISCH	ID03445.3p-miR	31	−125	88	24
32.2	ID01560.3p-miR	38	−123	89	23
32.2	ID03119.5p-miR	41	−125	88	24
MAPK3*	ID00149.3p-miR	1,144	−117	93	22
32.6	ID01748.3p-miR	1,144	−110	91	21
32.6	miR-6805-3p	1,145	−117	87	23
MAZ*	miR-6729-5p	361	−115	87	22
9.5	ID02623.3p-miR	363	−125	89	23
	ID02460.5p-miR	372	−119	92	22
	miR-2861	375	−110	95	19
	ID02294.5p-miR (3)	457 ÷ 469	−134 ÷−138	91 ÷ 94	24
	ID02986.5p-miR	459	−119	93	21
	ID01819.5p-miR	461	−125	87	25
	ID01804.3p-miR (2)	464 ÷ 467	−140	88	25
	ID02064.5p-miR	489	−121	92	21
	ID02538.3p-miR	489	−125	94	22
	ID00296.3p-miR	500	−138	88	25
	ID01641.3p-miR	506	−132	89	24
	miR-3960	505	−119	95	20
	miR-4706	605	−123	87	25
	ID01705.3p-miR	608	−117	92	21
	ID01641.3p-miR	608	−134	90	24
	miR-3960	612	−117	93	20
	ID01768.3p-miR	893	−113	90	22
	ID01911.5p-miR	900	−123	89	23
	ID00849.3p-miR	901	−125	97	22
BRCA2**	ID00112.5p-miR	10,722	−102	91	21
0.1	ID02744.3p-miR	10,738	−104	92	22
0.1	miR-619-5p	10,746	−117	96	22
CDK6**	miR-548h-3p	1,677	−104	91	23
2.2	miR-548z	1,677	−104	91	23
	miR-548aq-3p	1,678	−102	94	22
	miR-548az-3p	1,678	−98	94	21
	ID03264.3p-miR	1,678	−98	90	22
	miR-466 (10)	1,908 ÷ 1,926	−104 ÷−108	90 ÷ 93	23
	ID01030.3p-miR (7)	1,900 ÷ 1,918	−108 ÷−115	89 ÷ 95	23
	ID00436.3p-miR (9)	1,896 ÷ 1,920	−104 ÷−106	89 ÷ 91	23
	ID02513.5p-miR	1,901	−102	91	22

Notes.

Genes without *—miRNA binding sites are in the 5′UTR, genes with *—miRNA binding sites are in the CDS, **—miRNA binding sites are in the 3′UTR; values in parentheses indicate the number of binding sites; ÷—the change of the parameter in the interval. Different repeating clusters of miRNA binding sites in different genes are coloured.