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Change in C-statistic with 95% confidence intervals for composite fatal/non-fatal cardiovascular disease, fatal cardiovascular disease or all-cause mortality upon addition of each estimated glomerular filtration rate (eGFR) method: eGFR based on creatinine (eGFRcr), eGFR based on cystatin C (eGFRcys) and eGFR based on creatinine and cystatin C (eGFRcr-cys). The centre line (0.00) represents no change to C-index.
