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| Pharmacokinetic property | Details |
|---|---|
| Absorption | |
| Bioavailability | 9–19% |
| Time to peak plasma concentration | 1–3 h |
| Time to reach steady state | 7 days |
| Distribution | |
| Protein binding (serum proteins) | ~ 99% |
| Metabolism | |
| Route | Hepatic; CYP3A4-mediated |
| Elimination | |
| Route | Faeces (80%); urine (9%) |
| Elimination half-life | 20–40 h |
CYP Cytochrome P450
