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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Neurobiol Aging. 2019 Aug 15;83:54–62. doi: 10.1016/j.neurobiolaging.2019.08.011

Fig. 2.

Fig. 2.

Plots of age-adjusted FA and MD from entorhinal WM and the estimated or actual proximity to symptom onset. In the horizontal axis, 0 indicates the estimated age of symptom onset for asymptomatic MAPT mutation carriers based on the median age at the symptom onset in symptomatic MAPT mutation carriers from the same family. 0 indicates the age at actual symptom onset in symptomatic MAPT mutation carriers. Abbreviations: FA, fractional anisotropy; MD, mean diffusivity; MAPT, microtubule-associated protein tau; WM, white matter.