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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Metab Brain Dis. 2019 Aug 13;34(6):1705–1712. doi: 10.1007/s11011-019-00476-3

Fig. 3. Anti-PDL2 decreases activated splenic macrophages in male mice but not in female mice.

Fig. 3

Male mice treated with anti-PDL2 neutralizing antibody 4 h post-MCAO did not have any significant differences in the frequency of anti-inflammatory splenic macrophages as indicated by the frequency of CD11b+ Arg-1+ cells (a) or CD11b+ CD206+ cell (b). There was a significant decrease in the frequency of pro-inflammatory CD11b+ CD86+ cells in the spleens of anti-PDL2 neutralizing antibody treated mice (n = 15) compared to vehicle treated mice (n = 21) 96 h post-MCAO (c). *p < 0.05