Figure 3:

Biologic landscape in primary prostate cancer of low AR-active tumors. A. PAM50 subtypes of prostate cancer (Zhao et al; Basal, Luminal A, and Luminal B) by decile of AR-A. B. Analysis of AR-A decile and distribution of immune cell content, DNA repair, and neuroendocrine marker expression. Additional neuroendocrine markers shown in supplementary table S3.

Abbreviations: DSBR, double strand break repair; MDSC, Myeloid derived suppressor cells; MMR, mismatch repair; NEPC, neuroendocrine prostate cancer; Treg, Regulatory T-cell