Table 3.
PFS and OS by PET response dichotomy based on SUVmean valuesb
| Progression-free survival (PFS) | |||||
|---|---|---|---|---|---|
| N | Events | Point estimate | 80% Confidence interval | ||
| Lower limit | Upper limit | ||||
| Non-responders | |||||
| Median | 7 | 5 | 3.7 years | 0.3 years | 11.6 years |
| 1-year rate | 68% | 40% | 85% | ||
| 3-year rate | 57% | 29% | 77% | ||
| 5-year rate | 33% | 12% | 57% | ||
| 10-year rate | 22% | 6% | 46% | ||
| Responders | |||||
| Median | 9 | 5 | 7.9 years | 0.0 years | N/A |
| 1-year rate | 70% | 46% | 85% | ||
| 3-year rate | 63% | 39% | 79% | ||
| 5-year rate | 58% | 35% | 76% | ||
| 10-year rate | 42% | 20% | 65% | ||
| Overall survival (OS) | |||||
| N | Events | Point estimate | 80% Confidence interval | ||
| Lower limit | Upper limit | ||||
| Non-responders | |||||
| Median | 7 | 4 | 5.0 years | 0.0 years | N/A |
| 1-year rate | 70% | 42% | 86% | ||
| 3-year rate | 63% | 36% | 81% | ||
| 5-year rate | 51% | 25% | 71% | ||
| 10-year rate | N/A | N/A | N/A | ||
| Responders | |||||
| Median | 9 | 6 | 7.5 years | 0.8 years | 13.5 years |
| 1-year rate | 88% | 65% | 96% | ||
| 3-year rate | 64% | 40% | 80% | ||
| 5-year rate | 59% | 36% | 76% | ||
| 10-year rate | 39% | 19% | 60% | ||
N/A not applicable
b
PFS progression-free survival, OS overall survival, PET positron emission tomography, SUVmean mean standardized uptake value, Events death for overall survival; death or progression for progression-free survival