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. 2019 Nov 13;11:683–694. doi: 10.2147/CEOR.S222879

Table 4.

Cost Per Treatment Cycle

Treatments Cost/Cycle
1st line chemotherapy: intervention therapy
Induction (cytarabine + daunorubicin + midostaurin) € 6,521.41
Consolidation (high dose cytarabine + midostaurin) € 6,859.79
Maintenance (midostaurin) € 12,813.65
1st line chemotherapy: Comparator treatment
7 + 3 (cytarabine + daunorubicin)
€ 114.59
High dose cytarabine € 452.97
2nd line chemotherapy
FLAG-IDA (fludarabine + cytarabine + idarubicin)
€ 1,340.81
MEC (mitoxantrone + etoposide + cytarabine)
€ 514.44
Other treatmentsa
7 + 3 (cytarabine + idarubicin)
€ 786.53

Notes: aIn the opinion of experts, regimens based on cytarabine and idarubicin are also common in induction therapy in Spain, so a sensitivity analysis was carried out that included the costs of induction therapy with idarubicin and daunorubicin.