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Table 1. Baseline and procedural characteristics in the Global SYMPLICITY Registry-Taiwan.

Characteristics Symplicity FlexTM System (N = 8) Symplicity SpyralTM System (N = 18) p-value
Office systolic blood pressure, mmHg 0.68
 Median (IQR) 173.67 (152.50, 175.34) 173.34 (163.67, 181.67)
Office diastolic blood pressure, mmHg 0.24
 Median (IQR) 96.34 (83.17, 107.00) 87.00 (75.00, 99.67)
Heart rate (beats per minute) 0.49
 Median (IQR) 69.50 (65.34, 82.50) 68.50 (63.00, 74.00)
Age, years 0.23
 Median (IQR) 48.00 (43.50, 64.50) 61.00 (54.00, 68.00)
Male gender 87.5% (7/8) 61.1% (11/18) 0.36
Body mass index, kg/m2 0.17
 Median (IQR) 32.20 (28.60, 34.90) 28.70 (26.60, 31.00)
Obesity (≥ 30 kg m-2) 75.0% (6/8) 33.3% (6/18) 0.09
Smoking/tobacco use 25.0% (2/8) 16.7% (3/18) 0.63
Diabetes mellitus type 2 50.0% (4/8) 50.0% (9/18) 1.00
Renal insufficiency (eGFR < 60 ml/min/1.73 m2) 12.5% (1/8) 11.1% (2/18) 1.00
History of atrial fibrillation 12.5% (1/8) 5.6% (1/18) 0.53
Previous stroke 0.0% (0/8) 5.6% (1/18) 1.00
Previous myocardial infarction 0.0% (0/8) 5.6% (1/18) 1.00
Angina pectoris 25.0% (2/8) 5.6% (1/18) 0.22
Heart failure 12.5% (1/8) 11.1% (2/18) 1.00
Denervation procedure
 Procedure time (min) 0.13
  Median (IQR) 144.50 (118.50, 161.50) 107.50 (85.00, 158.00)
 Denervation time (min) 0.02
  Median (IQR) 103.50 (66.50, 113.00) 58.00 (37.00, 76.00)
 Number of ablations 0.01
  Median (IQR) 19.50 (13.50, 25.50) 40.50 (21.00, 54.00)
 Amount of contrast (ml) 0.87
  Median (IQR) 200.00 (160.00, 212.50) 180.00 (100.00, 230.00)
 Hospital stay (day) 0.2
  Median (IQR) 2.50 (2.00, 3.50)0 2.00 (2.00, 2.00)

eGFR, estimated glomerular filtration rate; IQR, interquartile range.