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. 2019 Nov 15;39(11):BSR20180896. doi: 10.1042/BSR20180896

Figure 4. Suppressing ENO1 counteracts the effect of LncRNA P5848.

Figure 4

(A) Knockdown of ENO1 suppresses the cell growth promoting effect of LncRNA P5848. (B) Knockdown of LncRNA P5848 induces cell apoptosis and knockdown of ENO1 further enhances this effect. (C) Representative blots showing the expression level of BAX, Bcl-2, Cleaved caspase-3. β-actin functions as an internal loading control. ENO1 increases the expression level of anti-apoptotic protein Bcl-2 and reduces caspase-3 cleavage, while decreasing the level of pro-apoptotic protein BAX. (D) Knockdown of ENO1 or LncRNA P5848 suppresses the cell migration.