Table 2. Univariate and multivariate Cox regression analyses of overall survival in GC patients.

Parameter	Univariate analysis			Multivariate analysis
	HR	95% CI	P	HR	95% CI	P
Gender
(Male vs. Female)	0.875	0.549–1.392	0.572
Age
(≥50 vs. <50)	1.158	0.730–1.837	0.533
Clinical stage
(III-IV vs. I-II)	4.524	2.635–7.770	<0.001	2.978	0.876–10.126	0.081
Tumor depth
(T3-T4 vs. T1-T2)	2.109	1.323–3.362	0.002	1.773	1.072–2.932	0.026
Lymph node metastasis
(N2-N3 vs. N0-N1)	4.233	2.500–7.167	<0.001	1.120	0.328–3.824	0.856
Distant metastasis
(M1 vs. M0)	13.301	5.256–33.656	<0.001	8.535	3.034–24.009	<0.001
BCYRN1
(Low vs. High)	3.125	1942–5.030	<0.001	2.047	1.185–3.534	0.010

Abbreviations: HR, hazard ratio; 95% CI, 95% confidence interval.