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. 2019 Nov 13;12:9585–9598. doi: 10.2147/OTT.S215674

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© 2019 Fan et al.

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Coronin3 promoted NPC cell growth both in vitro and in vivo. (A) The mRNA expression of coronin3 was estimated by qPCR after lentivirus transduction. Lentivirus with pLV-EGFP or pGCsil-GFP was used for overexpressing or knockdown. Null vectors were used as controls. ***p<0.001. n=3 per group, three repeats per time. (B) The protein expression of coronin3 was estimated by Western Blotting. (C) NPC cell viability was measured by MTT assay after stable lentivirus transduction. **p<0.01; ***p<0.001. n=6 per group. (D) Subcutaneous tumorigenicity to assess the effect of coronin3 on NPC cell growth in vivo. *p<0.05; **p<0.01. n=6 per group.