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. 2019 Nov 12;12:9559–9568. doi: 10.2147/OTT.S225294

Table 1.

The Relationship Between The Preoperative AAPR And Clinicopathological Variables

Variables Total (n=230) AAPR <0.68 AAPR ≥0.68 P-value
Age
≤55 years 115 (50%) 52 (45.2%) 63 (54.8%) <0.001*
>55 years 115 (50%) 89 (77.4%) 26 (22.6%)
menopause
No 98 (42.6%) 41 (41.8%) 57 (58.2%) <0.001*
Yes 132 (57.4%) 100 (75.8%) 32 (24.2%)
FIGO stage
IB 201 (87.4%) 120 (59.7%) 81 (40.3%) 0.189
IIA 29 (12.6%) 21 (72.4%) 8 (27.6%)
Pathological type
SCC 192 (83.5%) 123 (64.1%) 69 (35.9%) 0.054
No-SCC 38 (16.5%) 18 (47.4%) 20 (52.6%)
Tumor Size
≤2cm 113 (49.1%) 73 (64.6%) 40 (35.4%) 0.313
>2cm 117 (50.9%) 68 (58.1%) 49 (41.9%)
Histologic grade
I-II 124 (53.9%) 81 (65.3%) 43 (34.7%) 0.176
III 106 (46.1%) 60 (56.6%) 46 (43.4%)
Depth of invasion
<2/3 172 (74.8%) 99 (57.6%) 73 (42.4%) 0.045*
≥2/3 58 (25.2%) 42 (72.4%) 16 (27.6%)
LVSI
No 200 (87.0%) 123 (61.5%) 77 (38.5%) 0.875
Yes 30 (13.0%) 18 (60%) 12 (40%)
LNM
No 196 (85.2%) 121 (61.7%) 75 (38.3%) 0.748
Yes 34 (14.8%) 20 (58.8%) 14 (41.2%)
Vaginal invasion
No 218 (94.8%) 133 (61.0%) 85 (39.0%) 0.770
Yes 12 (5.2%) 8 (66.7%) 4 (33.3%)
Adjuvant therapy
No 84 (36.5%) 56 (66.7%) 28 (33.3%) 0.419
Chemoradiotherapy 57 (24.8%) 31 (54.4%) 26 (45.6%)
Chemotherapy 84 (36.5%) 50 (59.5%) 34 (40.5%)
Radiotherapy 5 (2.2%) 4 (80%) 1 (20%)
ALB(g/L) 46.3±4.2 46.0±4.4 46.8±4.0 0.141
ALP(U/L) 81.3±57.0 97.8±67.3 55.1±10.5 <0.001*

Notes: Independent-Samples T test or Mann–Whitney U-test was employed for continuous variables. Chi-squared test or Fisher’s exact test was employed for categorical variables. *P<0.05.

Abbreviations: AAPR, albumin/alkaline phosphatase ratio; FIGO, International Federation of Gynecology and Obstetrics; SCC, squamous cell carcinoma; LVSI, lympho-vascular space invasion; LNM, lymph node metastasis; ALB, albumin; ALP, alkaline phosphatase.