Table 1.
Box–Behnken design and the response for the extraction yield and the content of cormarin, cinnmic acid, cinnamaldehyde, and cinnamyl alcohol from Cinnamomum cassia blume by subcritical extraction process
| Run no. | Independent variables | Dependent variables (%) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Coded values | Uncoded values | ||||||||||
| X1 | X2 | X3 | X1 (°C) | X2 (min) | X3 (bar) | Y1 | Y2 | Y3 | Y4 | Y5 | |
| 1 | − 1 | − 1 | 0 | 110 | 20 | 40 | 7.61 | 15.02 | 4.91 | 53.73 | 4.49 |
| 2 | 1 | − 1 | 0 | 130 | 20 | 40 | 12.79 | 8.34 | 2.86 | 23.00 | 3.32 |
| 3 | − 1 | 1 | 0 | 110 | 60 | 40 | 10.22 | 12.87 | 4.14 | 45.23 | 3.92 |
| 4 | 1 | 1 | 0 | 130 | 60 | 40 | 15.11 | 7.54 | 2.74 | 15.75 | 3.24 |
| 5 | − 1 | 0 | − 1 | 110 | 40 | 20 | 9.35 | 15.53 | 4.62 | 53.68 | 4.29 |
| 6 | 1 | 0 | − 1 | 130 | 40 | 20 | 13.99 | 7.84 | 2.68 | 18.29 | 3.15 |
| 7 | − 1 | 0 | 1 | 110 | 40 | 60 | 8.83 | 13.78 | 4.46 | 41.49 | 4.05 |
| 8 | 1 | 0 | 1 | 130 | 40 | 60 | 13.45 | 6.80 | 2.50 | 17.46 | 3.04 |
| 9 | 0 | − 1 | − 1 | 120 | 20 | 20 | 9.79 | 12.29 | 3.65 | 37.89 | 3.69 |
| 10 | 0 | 1 | − 1 | 120 | 60 | 20 | 11.70 | 8.88 | 3.13 | 19.91 | 3.36 |
| 11 | 0 | − 1 | 1 | 120 | 20 | 60 | 11.64 | 9.96 | 3.27 | 25.67 | 3.37 |
| 12 | 0 | 1 | 1 | 120 | 60 | 60 | 11.78 | 9.80 | 3.35 | 25.71 | 3.47 |
| 13 | 0 | 0 | 0 | 120 | 40 | 40 | 13.03 | 9.34 | 3.59 | 38.50 | 2.92 |
| 14 | 0 | 0 | 0 | 120 | 40 | 40 | 11.52 | 9.80 | 3.99 | 35.05 | 2.91 |
| 15 | 0 | 0 | 0 | 120 | 40 | 40 | 10.62 | 8.98 | 3.83 | 40.66 | 2.86 |
X1 = extraction temperature (°C), X2 = extraction time (min), X3 = extraction pressure (bar), Y1 = extraction yield (%), Y2 = content of coumarin (%), Y3 = content of cinnamic acid (%), Y4 = content of cinnamaldehyde (%), Y5 = content of cinnamyl alcohol (%)