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. 2019 Nov 12;12:2341–2354. doi: 10.2147/DMSO.S219524

Table 4.

Hazard Ratios Of Association Between Current Shift Workers And Type 2 Diabetes For The Imputed And Unimputed Datasets, Stratified By Gender

Shift-work status Case/N PYs IRs/ 1000 PYs 95% CI Type 2 Diabetes Vs Normal
Unadjusted Adjusted Model 1 Adjusted Model 2
HR 95% CI HR 95% CI HR 95% CI
IMPUTED DATASET
Overall 154/5947 32,534 4.73 4.02–5.54
 Day workers 97/4095 21,642 4.48 3.63–5.47 1.00 1.00 1.00
 Former shift workers 10/599 3289 3.04 1.46–5.59 0.67 0.35–1.29 0.82 0.42–1.57 0.72 0.37–1.40
 Current shift workers 47/1253 7603 6.18 4.54–8.22 1.33 0.94- 1.89 1.82 1.27- 2.60 1.85 1.27–2.69
Female 101/4647 25,611 3.94 3.21–4.79
 Day workers 62/3049 16,148.5 3.84 2.94–4.92 1.00 1.00 1.00
 Former shift workers 7/491 2720.5 2.57 1.03–5.30 0.66 0.30–1.45 0.81 0.37–1.78 0.59 0.26–1.36
 Current shift workers 32/1107 6742 4.75 3.25–6.70 1.20 0.78–1.83 1.50 0.97–2.33 1.52 0.98–2.36
Male 53/1300 6923 7.66 5.73–10.01
 Day workers 35/1046 5493.5 6.37 4.44–8.86 1.00 1.00 1.00
 Former shift workers 3/108 568.5 5.28 1.09–15.42 0.83 0.25–2.69 0.80 0.25–2.61 1.02 0.31–3.34
 Current shift workers 15/146 861 17.42 9.75–28.73 2.66 1.45–4.87 2.77 1.51–5.08 2.98 1.58–5.62
p-interaction 0.1067 0.2666 0.1960
UNIMPUTED DATASET
Overall 154/5947 32,534 4.73 4.02–5.54
 Day workers 97/4095 21,642 4.48 3.63–5.47 1.00 1.00 1.00
 Former shift workers 10/599 3289 3.04 1.46–5.59 0.67 0.35–1.29 0.79 0.40–1.58 0.72 0.35–1.45
 Current shift workers 47/1253 7603 6.18 4.54–8.22 1.33 0.94–1.89 1.91 1.33–2.75 2.05 1.40–3.02
Female 101/4647 25,611 3.94 3.21–4.79
 Day workers 62/3049 16,148.5 3.84 2.94–4.92 1.00 1.00 1.00
 Former shift workers 7/491 2720.5 2.57 1.03–5.30 0.66 0.30–1.45 0.75 0.32–1.76 0.57 0.24–1.37
 Current shift workers 32/1107 6742 4.75 3.25–6.70 1.20 0.78–1.83 1.58 1.01–2.45 1.68 1.07–2.63
Male 53/1300 6923 7.66 5.73–10.01
 Day workers 35/1046 5493.5 6.37 4.44–8.86 1.00 1.00 1.00
 Former shift workers 3/108 568.5 5.28 1.09–15.42 0.83 0.25–2.69 0.85 0.26–2.77 1.13 0.34–3.73
 Current shift workers 15/146 861 17.42 9.75–28.73 2.66 1.45–4.87 2.93 1.59–5.41 3.32 1.73–6.35
p-interaction 0.1067 0.2691 0.1845

Notes: Model 1, Adjusted for age at baseline (years), family history of DM (no/yes), BMI at baseline (kg/m2), hypertension at baseline (yes; SBP ≥140 mmHg and/or DBP ≥90 mmHg/no). Model 2, model 1 additional adjusted for FPG at baseline (mg/dL), WBC at Baseline (cells/µL), TG at baseline (mg/dL), HDL-C at baseline (mg/dL), WC at baseline (cm), marital status (single or divorce/married), education level (≤12 years/>12 years).

Abbreviations: N, Number; PYs, person-years; IR, incidence rates; 95% CI, 95% confidence intervals; HR, hazard ratio.