Table 1.
Characteristics of SCLC patients with bone metastases at initial diagnosis.
| Subgroups | Number of patients (%) |
|---|---|
| Gender | |
| Female | 20 (19.6) |
| Male | 82 (80.4) |
| Age | |
| <65 | 71 (69.6) |
| ≥65 | 31 (30.4) |
| Smoke | |
| Yes | 83 (81.4) |
| No | 19 (18.6) |
| KPS | |
| <80 | 12 (11.8) |
| ≥80 | 90 (88.2) |
| Coexisting with extraosseous metastases | |
| No | 47 (46.1) |
| Yes | 55 (53.9) |
| Number of bone metastases | |
| Single | 26 (25.5) |
| Multiple | 76 (74.5) |
| Appendicular bone metastases | |
| Yes | 45 (44.1) |
| No | 57 (55.9) |
| Number of vertebra metastases | |
| <3 | 68 (66.7) |
| ≥3 | 34 (33.3) |
| T stage | |
| T1 | 5 (4.9) |
| T2 | 78 (76.5) |
| T3 | 15 (14.7) |
| T4 | 4 (3.9) |
| N stage | |
| N0 | 2 (2.0) |
| N1 | 8 (7.8) |
| N2 | 56 (54.9) |
| N3 | 36 (35.3) |
| Supraclavicular lymph nodes metastases | |
| Yes | 34 (33.3) |
| No | 68 (66.7) |
| Location of extraosseous metastases | |
| Liver | 25 (24.5) |
| Brain | 11 (10.8) |
| Adrenals | 7 (6.9) |
| Abdominal lymph node | 4 (3.9) |
| Skin | 1(1.0) |
| Pleural/chest wall | 8 (7.8) |
| Pancreas | 2 (2.0) |
| Contralateral lung | 8 (7.8) |
| LDH level | |
| Normal | 47 (46.1) |
| Elevated | 55 (53.9) |
| ALP level | |
| Normal | 87 (85.3) |
| Elevated | 15 (14.7) |
Abbreviations: LDH= lactate dehydrogenase; ALP= alkaline phosphatase