Table 1.
Characteristics and Outcomes of Patients With and Without ≥ 2 qSOFA Criteria on Admission
| Characteristics and Outcomes | ≥ 2 qSOFA |
< 2 qSOFA |
|---|---|---|
| (n = 271,500) | (n = 732,847) | |
| Median age, y (IQR) | 65 (51-78) | 58 (40-72) |
| Male sex,a No. (%) | 121,192 (44.6) | 299,704 (40.9) |
| Race,b No. (%) | ||
| White | 211,928 (78.1) | 538,385 (73.5) |
| Black | 38,745 (14.3) | 123,164 (16.8) |
| Other | 20,827 (7.7) | 71,298 (9.7) |
| Median AHRQ Elixhauser scorec (IQR) | 5 (0-14) | 0 (–1 to 8) |
| Elixhauser comorbidities, No. (%) | ||
| Chronic lung disease | 64,238 (23.7) | 117,696 (16.1) |
| Congestive heart failure | 48,874 (18.0) | 70,672 (9.6) |
| Diabetes,d | 68,372 (25.2) | 162,769 (22.2) |
| Neurologic disease | 45,179 (16.6) | 58,472 (8.0) |
| Cancere | 19,799 (7.3) | 38,695 (5.3) |
| Renal failuree | 39,629 (14.6) | 76,362 (10.4) |
| Median SOFA score on admission (IQR) | 5 (0-14) | 1 (0-2) |
| Median hospital LOS, d (IQR) | 5 (3-8) | 4 (2-5) |
| Required ICU admission,e No. (%) | 77,252 (28.5) | 47,299 (6.5) |
| Median ICU LOS, d (IQR) | 3 (2-5) | 2 (1-4) |
| In-hospital mortality, No. (%) | 18,141 (6.7) | 5,605 (0.8) |
All comparisons between the qSOFA+ vs qSOFA– groups were statistically significant, with P < .001. AHRQ = Agency for Healthcare Research and Quality; IQR = interquartile range; LOS = length of stay; qSOFA = Quick Sequential Organ Failure Assessment; SOFA = Sequential Organ Failure Assessment.
Sex was missing for 128 patients (0.01%).
Race was missing for 16,860 patients (1.7%).
The AHRQ Elixhauser Comorbidity Index score is weighted and allows for negative points for comorbidities with an inverse association with mortality.
Diabetes comorbidity includes diabetes with and without complications.
Cancer comorbidity includes solid tumor, metastatic cancer, and lymphoma.