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. 2019 May 9;28(19):3175–3187. doi: 10.1093/hmg/ddz118

Figure 3.

Figure 3

Motor neuronal overexpression of CIP improves motor neuron survival in TriTg mice. (A) Representative images of Nissl-stained motor neurons in matching lumbar spinal cord cross-sections at Day 150. (B and D) Motor neuron survival counts in lumbar spinal cord cross-sections at Day 150; values are mean ± SEM (n = 3–4 per genotype; **P < 0.001, ***P < 0.0001; one-way ANOVA, with Tukey’s post hoc tests). Scale bar = 100 mm. Immunohistochemical staining for Chat (motor neuronal marker) and FLAG for CIP, in the spinal cord demonstrating CIP expression in motor neurons at Day 150. Scale bar = 30 mm (C).