Figure 7.
Effect of miR-183-5p.1 overexpression on the expression of apoptosis-associated proteins in GC AGS cells as detected by western blot analysis. (A and B) P53 was decreased and Bcl-2 was increased in the miR-183-5p.1 mimic-transfected cells. (C and D) miR-183-5p.1 inhibitors significantly inhibited the expression of Bcl-2, but significantly enhanced the expression of p53. GAPDH was used as the internal control. Results are presented as the mean ± standard error of the mean (n=3). ***P<0.001. GC, gastric cancer; miR, microRNA.