Table 3.

Hazard ratios for the combined associations of hs-CRP and cognitive impairment with all-cause mortality (N = 1447)

Groups/HR	No. of deaths	Model 1	Model 2a
1: hs-CRP ≤ 3.0 mg/L and normal cognition	312	1	1
2: hs-CRP > 3.0 mg/L and normal cognition	117	1.80 (1.24, 2.61)	1.70 (1.13, 2.56)
3: hs-CRP ≤ 3.0 mg/L and CI	286	2.79 (1.82, 4.28)	2.39 (1.61, 3.55)
4: hs-CRP > 3.0 mg/L and CI	111	4.61 (3.16, 6.72)	3.56 (2.35, 5.38)
P for trend	–	< 0.001	< 0.001

Model 1 adjusted for age and sex; model 2 further adjusted for drinking, smoking, marital status, regular exercise, medication, BMI, central obesity, self-reported history of hypertension, diabetes mellitus, heart disease, stroke and cerebrovascular disease, respiratory disease and cancer. CI = cognitive impairment

^a P for interaction< 0.01