Table 4.

Difference in means between treatment and control groups for TC at final follow-up

Author	Sample size (treatment group vs. control group)	Difference	95% CI
Cabral et al. [57]	32 (14 vs. 18)	− 1.07 mmol/L*	− 2.49 to 0.36
Caraccio et al. [58]	49 (24 vs. 25)	− 0.30 mmol/L*	− 0.92 to 0.32
Duman et al. [60]	39 (20 vs. 19)	0.00 mmol/L*	− 0.98 to 0.98
Iqbal et al. [62]	64 (32 vs. 32)	− 0.10 mmol/L*	− 0.59 to 0.39
Liu et al. [64]	119 (60 vs. 59)	− 0.29 mmol/L**	− 0.54 to − 0.04
Mikhail et al. [66]	120 (60 vs. 60)	− 0.30 mmol/L*	− 0.58 to − 0.30
Monzani et al. [68]	45 (23 vs. 22)	− 1.56 mmol/L*	− 2.91 to − 0.20
Nagasaki et al. [69]	95 (48 vs. 47)	− 0.14 mmol/L**	− 0.54 to 0.26
Teixeira et al. [74, 75]	26 (11 vs. 15)	− 0.32 mmol/L*	− 1.79 to 1.16

*Value is the difference in mean scores at final follow-up between treatment and control groups

**Value is the difference in mean variation scores from baseline to follow-up between treatment and control group