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. 2019 May 17;21(6):598–604. doi: 10.4103/aja.aja_29_19

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Kaplan–Meier analyses of BCR-free survival rates. (a) Comparison of upgraded and nonupgraded patients in Gleason score (3+3) cohort. The 5-year BCR-free survival rate was statistically significantly lower in the upgraded group (100.0% vs 96.7%, P = 0.047). (b) Comparison of downgraded and nondowngraded patients in Gleason score (4+4) cohort. The 5-year BCR-free survival rate was detected significantly higher in the downgraded group (71.1% vs 50.8%, P = 0.032). ^*P < 0.05 was considered statistically significant. BCR: biochemical recurrence.