Figure 2.

Effect of ginsenosides on differentiation and function of myeloid-derived suppressor cells (MDSCs) in tumor microenvironment.

In tumor microenvironment, MDSCs from immature myeloid cells inhibit the antitumor ability of T cells. In each process, ginsenosides play a negative role. KRG, Korean Red Ginseng; C-K, ginseng-derived compound K; SQF, Sheng Qi formula. Blue lines demonstrated the promotion () or inhibition () roles among immature myeloid cells, MDSCs, and T cells. Yellow lines indicated the promotion () or inhibition () roles of ginsenosides.