Table 3.
Differences between global brain network parameters of BSP patients, HFS patients and HC (group) at baseline and after treatment with BoNT (time). The rmANOVA with dependent measures of global network parameters (modularity, clustering, local efficiency, path length, and global efficiency), and group (BSP, HFS) and time (pre, post) as independent main effects.
| Clinical score | Sum of squares | (df intercept, df error) | F | p | |
|---|---|---|---|---|---|
| Modularity | Group | 0.14 | (1, 40) | 192.9 | <0.001 |
| Time | 0.17 | (1, 40) | 712.1 | <0.001 | |
| Group × Time | 0.00 | (1, 40) | 12.9 | <0.001 | |
| Clustering | Group | 0.25 | (1, 40) | 311.7 | <0.001 |
| Time | 0.00 | (1, 40) | 1.97 | >0.1 | |
| Group × Time | 0.009 | (1, 40) | 222.1 | <0.001 | |
| Local efficiency | Group | 0.10 | (1, 40) | 168.0 | <0.001 |
| Time | 0.001 | (1, 40) | 10.3 | <0.01 | |
| Group × Time | 0.001 | (1, 40) | 18.1 | <0.001 | |
| Path length | Group | 1.06 | (1, 40) | 51.9 | <0.001 |
| Time | 0.21 | (1, 40) | 608.7 | <0.001 | |
| Group × Time | 0.16 | (1, 40) | 483.6 | <0.001 | |
| Global efficiency | Group | 0.15 | (1, 40) | 122 | <0.001 |
| Time | 0.16 | (1, 40) | 2894.6 | <0.001 | |
| Group × Time | 0.01 | (1, 40) | 2391.8 | <0.001 |