FIG. 5.
Fenofibrate attenuates peroxisomal dysfunction in WAT of HFD-fed WT mice. (A, B) Western blot analysis of Pex5, Pex14, and Pex16 protein expression in WAT. (C) Immunostaining and (D) fluorescence-intensity quantification of Abcd3. Original magnification: 200 × ; scale bar: 50 μm. (E) Measurement of peroxisomal FAO in WAT. (F, G) Western blot analysis of Abcd3, Acox1, and catalase protein expression in WAT. Expression levels of indicated proteins were quantified by densitometry and normalized with β-actin. (A–G) Values represent mean ± SE of seven mice. *p < 0.05. Color images are available online.