Figure 1. Clinical analyses of 78 TNBC biopsies from pCR and non-pCR patients before any treatment.

(A) API-5 immunostaining at x400 magnification in pCR and non pCR. The percentage of API-5 expression (right panel) in endothelial cells confirms high levels of API-5 expression in non-pCR biopsies. For the scoring, the percentage of positive cells in 100 cells was determined, and results were expressed as mean ± SEM. (B) Endothelial cells were labelled using CD34 antibody in pCR and non-pCR biopsies (left panel) at x200 magnification. The percentage of positive cells and vascular densities were determined as described in materials and methods (right panel).