. Author manuscript; available in PMC: 2019 Dec 1.

Published in final edited form as: Am J Med. 2018 Aug 1;131(12):1515.e11–1515.e19. doi: 10.1016/j.amjmed.2018.07.009

Table 3.

Relationship between 25(OH)D and Measures of Ventricular Function in HFpEF Patients (n = 97)

Outcome	Univariate^*		Multivariate^†
Outcome	Beta (SE)	P Value	Beta (SE)	P Value

Left ventricular mass (g)	−0.84 (0.70)	.233	0.28 (0.59)	.632
End diastolic volume (mL)	−0.32 (0.39)	.407	−0.05 (0.41)	.904
End systolic volume (mL)	−0.24 (0.17)	.151	−0.22 (0.18)	.227
Ejection fraction (%)	0.18 (0.16)	.274	0.27 (0.18)	.134
E/A ratio	0.003 (0.008)	.656	0.005 (0.008)	.563
(ln) BNP (pg/dL)	0.003 (0.014)	.813	0.003 (0.015)	.843

BNP = brain natriuretic peptide; E/A = ratio of early to late diastolic filling; HFpEF = heart failure with preserved ejection fraction; 25(OH)D = 25-hydroxyvitamin D.

Data analyzed using general linear regression and are presented as estimated change in outcome per ng/mL increment in 25(OH)D [Beta].

^†

Adjusted for age, sex, race, body mass index, and season.