Table 3.
The Expression Levels Of circBNC2, HE4, And CA125 With Regard To Histology, Menopause Status, And Tumor Stage
| Group | Total n = 249 | circBNC2, Median (Range) | HE4, pmol/L, Median (Range) | CA125, U/mL, Median (Range) |
|---|---|---|---|---|
| Epithelial ovarian cancer | n = 83 | 0.230 (0.081–0.511) | 175.1 (29.3–246.8) | 9.0 (2.1–52.9) |
| Pre-M | n = 44 | 0.250 (0.116–0.355) | 60.3 (29.3–215.8) | 8.1 (2.8–45.5) |
| Post-M | n = 39 | 0.204 (0.081–0.511) | 210.4 (57.2–246.8) | 12.5 (2.1–52.9) |
| Early stagea | n = 25 | 0.137 (0.120–0.511) | 60.3 (29.3–214.1) | 3.4 (2.3–45.5) |
| Late stagea | n = 58 | 0.230 (0.081–0.490) | 190 (39.4–246.8) | 11.2 (2.1–52.9) |
| Benign ovarian cyst | n = 83 | 0.680 (0.091–1.555) | 56.5 (38.1–189.3) | 16.4 (2.1–53.1) |
| Pre-M | n = 44 | 0.950 (0.092–1.555) | 49.2 (38.1–162.8) | 13.3 (3.2–52.1) |
| Post-M | n = 39 | 0.443 (0.091–1.450) | 64.6 (39.4–189.3) | 18.7 (2.1–53.1) |
| Normal cohort | n = 83 | 1.008 (0.155–1.932) | 53.1 (17.8–201.2) | 4.0 (1.0–43.1) |
| Pre-M | n = 44 | 1.040 (0.164–1.932) | 49.8 (22.4–184.4) | 4.1 (1.0–43.1) |
| Post-M | n = 39 | 0.928 (0.155–1.328) | 64.9 (17.8–201.2) | 3.9 (1.8–38.6) |
Note: aAccording to FIGO staging.
Abbreviations: M, menopause; n, number.