FIG. 2.
(a) Overlay of WDR5 cocrystal structures bound to the MLL peptide (3EG6,14 Ac-ARA-NH2 displayed), 1, and 2. Binding mode of (b) 1, (c) the MLL1 peptide, and (d) 2.
(a) Overlay of WDR5 cocrystal structures bound to the MLL peptide (3EG6,14 Ac-ARA-NH2 displayed), 1, and 2. Binding mode of (b) 1, (c) the MLL1 peptide, and (d) 2.