TABLE IV.

SAR of derivatives of 2.

Compound	R	KD (μM)a
13		> 3000
14		530b
15		300 ± 40
16		140 ± 30
17		22 ± 6
23		890b
24		240 ± 10
28		350 ± 40
29		200 ± 10
30		12 ± 1
31		25 ± 3
32		28.9 ± 0.5
35		11 ± 1
37		4.5 ± 0.3
40		19 ± 3
45		98.6 ± 0.6
47		24.2 ± 0.2

^amean ± SE.

^bSE not reported (n = 1).