Table 1. Basic characteristics of study population.
| Healthy controls |
Non-albinism FH |
Albinism FH |
||
|---|---|---|---|---|
| n (patients) | 15 | 10 | 13 | |
| Age (years) | 20.2 ± 3.17 | 20.72 ± 14.54 | 17.30 ± 10.16 | |
| Spherical equivalent (Dptr) | -0.55 ± 1.07 | -1.14 ± 3.59 | 0.53 ± 3.71 | |
| BCVA (LogMAR) | 0.07 ± 0.09 | 0.38 ± 0.27 | 0.42 ± 0.25 | |
| Major and minor criteria for albinism | ||||
| n (eyes) | 30 | 18 | 26 | |
| FH grade 1 | 0 | 2 | 0 | |
| FH grade 2 | 0 | 11 | 0 | |
| FH grade 3 | 0 | 3 | 23 | |
| FH grade 4 | 0 | 2 | 3 | |
| Fundus hypopigmentation | 0 | 6 | 24 | |
| Projection abnormality (VEP) | N/A | 0* | 6* | |
| Iris translucency | 0 | 0 | 24 | |
| Nystagmus | 0 | 4 | 16 | |
| Strabismus | 0 | 4 | 16 | |
| Mean GCLT (μm) | ||||
| nasal II | 37.93 ± 3.23 | 31.35 ± 8.10 | 38.27 ± 4.15 | |
| nasal I | 50.9 ± 5.24 | 41.40 ± 15.30 | 48.58 ± 2.79 | |
| central | 14.53 ± 3.73 | 27.75 ± 11.00 | 38.50 ± 4.67 | |
| temporal I | 47.1 ± 3.76 | 36.25 ± 12.34 | 35.2 ± 3.52 | |
| temporal II | 35.27 ± 3.05 | 27.50 ± 5.93 | 26.92 ± 1.90 | |
| p-values | ||||
| Albinism FH—Healthy controls | Albinism FH—Non-albinism FH | |||
| GCLT-I-Quotient | <0.001 | 0.004 | ||
| GCLT-II-Quotient | <0.001 | 0.006 | ||
Basic characteristics of study population, Dptr (Diopter), BCVA (best corrected visual acuity), LogMAR (logarithm of the minimum angle of resolution), FH (foveal hypoplasia), VEP (visual evoked potential), N/A (not available), GCLT (ganglion cell layer thickness), μm (micrometres)
*0 out of 1 and 6 out of 8, statistical significant p-values (< 0.0125) are marked in bold.