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. 2019 Nov 18;14(11):e0225133. doi: 10.1371/journal.pone.0225133

Table 6. Breastfeeding at 6–8 weeks (n = 38725).

Exposures Exposed n [%] Unexposed [n [%] Unadjusted OR
[95% CI]
Adjusted* OR [95% CI] NNH Interaction term with depression variable
SSRI [any N06AB] in trimesters 2 or 3 137/645 [21.24] 12,656/38,080 [33.24] 0.54 [0.45–0.66] 0.77 [0.62–0.95] 9 [712] 1.11(0.72–1.70)
SSRI high dose in trimesters 2 or 3 47/214 [21.96] 12,746/38,511 [33.1] 0.57 [0.41–0.79] 0.45 [0.23–0.86] 9 [618] 2.49[11.13–5.52]
Antidepressant [any N06A] in trimesters 2 or 3 179/806 [22.21] 12,614/37,919 [33.27] 0.57 [0.48–0.68] 0.81 [0.67–0.98] 10 [813] 1.25[0.86–1.83]
SSRI in trimester 1 but not in trimesters 2 or 3 207/862 [24.02] 12,586/37,863 [33.24] 0.64 [0.54–0.74] 0.66 [0.51–0.87] 11 [916] 1.59[1.10–2.30]
Antidepressant in trimester 1 but not in trimesters 2 or 3 376/1619 [23.22] 12,417/37,106 [33.46] 0.60 [0.54–0.68] 0.70 [0.57–0.85] 10 [913] 1.37[1.04–1.80]
Depression diagnosed and unmedicated in t2 and t3 1365/5241 [25.87] 11,428/33,484 [34.13] 0.68 [0.67–0.73] 0.87 [0.82–0.92] 13 [1115] Na
Depression medicated in t2 or t3 102/472 [21.62] 12,691/38,253 [33.18] 0.56 [0.45–0.69] 0.70 [0.58–0.85] 9 [713] Na
Depression diagnosed 1467/5713 [25.7] 11,346/33,012 [34.31] 0.66 [0.62–0.71] 0.76 [0.70–0.82] 12 [1114] Na

Exclusions, definitions and abbreviations as in Table 2

*Adjusted for SES, as Townsend fifth, parity, smoking and year of birth.