Table 5.

Summary of practical guidelines for invasive aspergillosis

Primary therapy	Salvage therapy
IV administration of voriconazole (6 mg/kg per 12 h at day 1 then 4 mg/kg per 12 h until improvement) followed by oral administration of voriconazole (200 mg per 12 h) or itraconazole (400–600 mg per 24 h) until resolution or stabilization of all clinical and radiological manifestations	IV administration of caspofungin (70 mg at day 1 then 50 mg) or IV administration of micafungin (100–150 mg per 24 h) until improvement followed by oral administration of voriconazole (200 mg per 12 h) or oral administration of itraconazole (400–600 mg per 24 h) until resolution or stabilization of all clinical and radiological manifestations
OR	OR
IV administration of l-amphotericin B (3–5 mg/kg per 24 h) followed by oral administration of voriconazole (200 mg per 12 h) or itraconazole (400–600 mg per 24 h) until resolution or stabilization of all clinical and radiographic manifestations	Posaconazole (200 mg per 6 h initially then 400 mg per 12 h orally after stabilization of disease)