Percent change in plasma adiponectin from baseline in Mexican‐American children who were either randomised to an intervention (n = 152; grey circles) or control (n = 69, black diamonds) group. Intervention subjects completed a 6‐month supervised intervention that consisted of 4 days week−1 of exercise (45 min day−1) and 1 day week−1 of nutritional counselling. Compared with baseline, at 6 months, the control group decreased by 80% and the intervention group decreased by 64%. Compared with baseline, at 12 months, the control group decreased by 50% and the intervention group decreased by 32%. Values % change ± standard error of the mean. *indicates greater than control group (P < 0.05).