Table 7.
Impact on growth outcomes of interventions in which complementary foods were fortified with additional micronutrients*
| Author | Site | Target group | Study groups | n | Weight | Length/height | % underweight | % stunted |
|---|---|---|---|---|---|---|---|---|
| Efficacy | ||||||||
| Adu‐Afarwuah et al. (2007) | Ghana | 6 months | SP or NT | 200 | −0.71 ± 1.10 | −0.42 ± 1.10 | ||
| No intervention | 96 | −0.74 ± 1.10 | −0.40 ± 1.00 | |||||
| ES: 0.03 (WAZ) | ES: −0.02 (LAZ) | |||||||
| Dhingra et al. (2004) | India | 12–36 months | Milk powder + micronutrients | 289 | 2.13 ± 0.58 † | 0.24 ± 0.45 † | ||
| Milk powder | 281 | 1.92 ± 0.55 | 0.05 ± 0.4 | |||||
| ES: 0.37 (Wt gain) | ES: 0.45 (LAZ change) | |||||||
| Faber et al. (2005) | South Africa | 6–12 months | Food + micronutrients | 145 | 10.7 ± 1.4 | 76.1 ± 3.3 | ||
| Food | 147 | 10.7 ± 1.6 | 75.7 ± 3.8 | |||||
| ES: 0 (Wt) | ES: 0.11 (Lt) | |||||||
| Giovannini et al. (2006) | Cambodia | 6 months | MMN Sprinkles™ | 65 | −1.25 ± 0.79 ‡ | −1.56 ± 1.0 § | ||
| Placebo | 62 | −1.08 ± 0.79 ‡ | −1.63 ± 1.0 § | |||||
| ES: −0.22 (WAZ) | ES: 0.07 (LAZ) | |||||||
| Lartey et al. (1999) | Ghana | 6 months | Fortified cereal/legume | 47 | 1.3 ± 0.5 | 7.0 ± 1.4 | ||
| Cereal/legume/fish | 143 | 1.2 ± 0.5 | 6.9 ± 1.2 | |||||
| ES: 0.20 (Wt gain) | ES: 0.08 (Lt gain) | |||||||
| Smuts et al. (2005) | South Africa | 6–12 months | Daily MMN foodlet | 49 | −0.25 ± 0.84 | −1.11 ± 0.98 | ||
| Placebo | 50 | −0.5 ± 0.91 | −1.16 ± 0.94 | |||||
| ES: 0.29 (WAZ change) | ES: 0.05 (LAZ) | |||||||
ES, effect size; LAZ, length‐for‐age z‐score; MMN, multiple micronutrients; SP or NT, Sprinkles or Nutritabs; WAZ, weight‐for‐age z‐score. *Weight (Wt) and length/height (Lt) refer to the growth outcome shown in parentheses (units: Wt in kg; Lt in cm), which is also the outcome that gave the largest effect size in studies that reported more than one weight or length outcome. Italicized SD values are estimates. †Means are significantly different (P < 0.05). ‡SD values are estimates from subjects of similar age from Vietnam (Schroeder et al. 2002). §SD values are estimates assuming that LAZ has N(0, 1) distribution.