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. Author manuscript; available in PMC: 2019 Nov 18.
Published in final edited form as: ACS Nano. 2018 May 16;12(6):5709–5718. doi: 10.1021/acsnano.8b01515

Table 1.

NBC System Evaluation Using ZIKV-Infected Patient Serum Samples (n = 10)a

CDC Zika MAC-ELISAb
Aptima Zika virus assayc
NBC systemd
Patient no. sample ISR value sample S/Co value sample V (μm/s)
1 positive 13.86 positive 18.51 positive 0.272
2 positive 14.96 negative 0.00 positive 0.253
3 positive 21.32 positive 31.91 positive 0.432
4 positive 3.78 positive 20.59 positive 0.208
5 positive 18.98 positive 32.91 positive 0.439
6 positive 17.25 negative 0.00 positive 0.372
7 positive 18.07 positive 33.09 positive 0.475
8 positive 14.14 positive 19.39 positive 0.246
9 positive 2.55 positive 17.18 positive 0.140
10 negative 0.60 negative 0.00 negative 0.065
a

The cellphone results were compared with the results obtained by the standard lab-based tests recommended for ZIKV detection.

b

Zika immune status ratio values (Zika ISR). Reading of ≥1.80 is positive and ≤1.60 is negative as defined by the manufacturer.

c

Signal-to-cutoff value (S/Co). Reading of >1.0 is positive and <1.0 is negative as defined by the manufacturer.

d

V is the velocity magnitude. Reading of ≥0.086 is positive and <0.086 is negative, considering S/N = 2 and the average velocity of control samples (no ZIKV) is 0.07 ± 0.008 μm/s.