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. 2019 Nov 10;4(1):e000396. doi: 10.1136/bmjophth-2019-000396

Table 4.

Clinical outcomes of patients with inflammatory or autoimmune keratitis undergoing lamellar patch graft surgery using gamma-irradiated corneal lenticules

Patient Age (years) Sex Indication for surgery Histopathology Duration of follow-up (months) Clinical outcome
19 80 Female Systemic lupus erythematosus with secondary Sjögren’s syndrome. Acute inflammation and necrosis, no e/o infection. 96 Never epithelialised, graft melted
<1 month. Underwent several subsequent tectonic PKs—all melted. Eventually cornea epithelialised, scarred and vascularised after achieving adequate immunosuppression.
20 81 Female Rheumatoid arthritis. Acute inflammation and necrosis, no e/o infection. 53 Graft intact and epithelialised, but developed other intraocular complications due to retinal surgery. Eventually eye became phthisical.
21 32 Male Sterile keratolysis with unknown aetiology. Acute inflammation and necrosis, no e/o infection. 36 Graft initially intact with under Gunderson conjunctival flap done simultaneously, then melted within 3 months. Underwent KPro implantation which failed. Eventually cornea scarred and KPro left in place.
22 75 Female Sterile keratolysis with unknown aetiology. Acute inflammation and necrosis, no e/o infection. 29 Graft intact, epithelialised and remained clear.
23 13 Female Sterile inflammatory corneal lesion with unknown aetiology. Stromal lymphoplasmacytic inflammation with granulomatous features. 8 Graft intact, epithelialised and remained clear.

e/o, evidence of; KPro, Boston type 1 keratoprosthesis; PK, penetrating keratoplasty.