Fig. 3.

Detection of vimentin expression in diverse Chr8 ploidy CTCs and correlation of Vim⁺ CTCs with PFS. A Vimentin expression in diverse Chr8 ploidy CTCs. a–e Vim⁺ CTCs with haploid, diploid, triploid, tetraploid, and multiploid Chr8, respectively. B Proportion of diverse Chr8 ploidy Vim⁺ CTCs in pretreatment patients. C Correlation of Vim⁺ CTCs with PFS. Patients with advanced lung cancer showing poor prognosis had positive detection of Vim⁺ CTCs (≥ 1/6 ml). Subgroup analysis showed the presence of Vim⁺ CTCs indicating worse prognosis in both SCLC and ADC patients