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. 2019 Nov 12;13:254. doi: 10.3389/fnbeh.2019.00254

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Copyright © 2019 Meir Drexler, Merz, Lissek, Tegenthoff and Wolf.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Day 1: Fear acquisition training. Mean (± SEM) SCR to the three conditioned stimuli (mean of 10 trials for CS+ and CS−). SCR to the reinforced CS+ are significantly higher (RE+CORT: 0.16 ± 0.03; RE: 0.17 ± 0.03; CORT: 0.24 ± 0.04) than the SCR to the unreinforced CS− (RE+CORT: 0.10 ± 0.02; RE: 0.14 ± 0.02; CORT: 0.18 ± 0.03; ***p < 0.001), demonstrating successful fear learning. The figure presents all three groups combined (N = 75; RE+CORT group: n = 25, RE group: n = 25, CORT group: n = 25) as no interaction and no main effect of group were found.